Synthetic α-MSH is also known as "Melanotan," Bodybuilders like to use it to give them the most ridiculous un-natural looking tans.
Natural Melanocyte Stimulating Hormones (MSH) are secreted by the pituitary gland and have been shown to have a positive effect on the intestinal barrier, potentially helping those people suffering from "leaky gut."
"A crucial role of receptor MC1R (a receptor that Alpha-MSH binds to) in inflammatory gut disease was demonstrated in *sophisticated* mouse models. (3)
We have seen other studies where narrowband UVB modulates the microbiome. So light touching the skin and eyes and then having a downstream direct effect on the gut comes again at no surprise. (1,2)
Shawn Bean has done extensive research on the microbiome and believes increasing MSH can heal intestinal permeability (Leaky Gut).
When you are lacking adequate sunlight you do not produce MSH.
“UVA rays increase the body's levels of melanocyte stimulating hormone (MSH), another hormone that stimulates the vagus nerve.
UVB rays increase the number of MSH receptors throughout the body making it possible for even more MSH to bind”.
Without MSH you will not be able to recover from leaky gut as the gap junctions will not seal.
In addition, If you are depleted of MSH then you may lose vagus tone.
Without proper vagus nerve tone your body cannot work optimally.
In conclusion, sunlight most definitely contributes to marked improvements in intestinal flora and is also likely to be beneficial for you on your path to heal your leaky gut.
Article Inspired by my Mentor Shawn Bean of Matrix Health and Wellness
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