The highest mitochondrial density is in the eyes. This makes the eyes very susceptible to damage from blue light and repair from red. Did you know that the eyes are actually part of the brain?
In 2018, researchers using an innovative illumination device measured the precise action spectrum of the oxidative stress mechanisms on A2E-loaded retinal pigment epithelium cells. (Simply, the scientists wanted to figure out which part of the light spectrum generated the most free radicals. Free radicals damage DNA, cell membranes and oxidize lipids.)
415-455 nm blue-violet light was determined to be the spectral band that generates the highest amount of reactive oxygen species (free radicals) and produces the highest level of mitochondrial dysfunction (root cause of many diseases).
In February 2018 researchers discovered "Blue light affects mitochondrial function and also the development tight junctions between ARPE19 cells, which results in a loss of cell viability.
Importantly, red light delivered after a blue light insult is significantly blunted
The conclusion was:
"These findings argue for the therapeutic use of red light as a noninvasive procedure to attenuate insults caused by blue light and other insults to retinal pigment epithelial cell mitochondria that are likely to occur in age‐related macular degeneration."
Another investigation in march 2019, published in Neurochemistry International, researchers showed that blue light caused oxidative stress and decreased cell survival.
But again that long-wavelength red light enhanced mitochondrial function, and that in turn increased survival of cultured retinal cells and reduced the effects of blue light.13
ref: www.reviewofoptometry.com › Blue Light Bad, Red Light Good for Mitochondria.
Again in March 2020 researchers published a study titled "Photobiomodulation Mediates Neuroprotection against Blue Light Induced Retinal Photoreceptor Degeneration”
Abstract: "Potent neuroprotective effects of photobiomodulation (red light therapy) with 670 nm red light (RL) have been demonstrated in several models of retinal disease. RL improves mitochondrial metabolism, reduces retinal inflammation and oxidative cell stress, showing its ability to enhance visual function."
Most recently. published on April 2nd 2020, A pilot study was conducted on humans showed a 20% increase in visual function in people with normal ageing eyes after 670 nm light was applied at 40 mW/cm2 or 4.8J/ cm2 for 2 min.
Unfortunately, in people with intermediate macular degeneration there was no improvement.
From this we may be able to infer that early detection and intervention is important.
Your team at EMR-TEK